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What determines female infertility?

letto 8358 volte | autore: Claudio Manna, ginecologo specialista in fecondazione assistita (vai al curriculum)


Infertility is defined as a condition where after a year of unprotected sexual intercourse pregnancy does not occur.

Infertility is considered : primary when one has never been pregnant, secondary when there are pregnancies that have been carried to term or that have ended in miscarriage.

The most important factors of infertility can be classified as follows:

  • Hormonal deficiencies and ovulation disturbances: when the temperature curve is abnormal, it is referred to as disovulation.  In the absence of ovulation, obviously, fertilisation cannot take place.
  • Blockage of the tubes or inadequate functionality of these; about a quarter of sterility is caused by obstruction of the uterine tubes also known as salpinges.  The principal causes of this problem can generally be traced back to previous  or current infections (salpingitis caused by gonococci, tuberculoses, chlamydia and other sexually transmitted germs, as well as common germs and previous extra-uterine pregnancies
  • Endometriosis, hyperplasia of the endometrium, fibroids, polyps
  • Malformation of the uterus : acquired or congenital stenosis of the uterine neck
  • Immunologic : the production of antibodies against the sperm of ones partner
  • Infections : endocervisitis
  • Ovarian abnormalities : agenesis and disgenesis
  • Genetic pathologies : chromosomal abnormalities, syndromes of genetic origin

More general causes:

  • alteration of the central nerves that regulate ovulation, the hypothalamus and the hypophysis, tumors
  • weight abnormalities : excessive thinness (for example anorexia), but above all if it is associated with taking part in very intense professional sport that can cause a-ovulation through perturbation of the pulsability of the gonadotropic hormones. Viceversa  obesity or rapid weight gain that is almost always accompanied by hormonal changes.

Disclaimer: the information provided on this site is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her existing physician.

giovedģ 20 marzo 2008

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